Ritonavir — What You Need to Know

Ritonavir is an antiviral used primarily to treat HIV. Doctors now often give it at low doses to boost other protease inhibitors by blocking CYP3A4, which slows the breakdown of those drugs. That boosting effect lets other antivirals stay at useful levels longer and can simplify dosing. If you see ritonavir listed, it's often part of a combination therapy rather than the main antiviral on its own.

Common side effects include nausea, diarrhea, and stomach discomfort. Some people notice changes in taste or a longer term rise in blood fats like triglycerides. Liver enzymes can increase, so doctors check liver tests before and during treatment. Weight gain and changes in body fat distribution have been reported with long-term use.

How it's used

Ritonavir comes as tablets and liquid. When used as a booster the dose is much lower than older standalone regimens. Your clinic will tell you exact dosing because it depends on the partner drug. Never change dose or stop suddenly without medical advice — stopping can affect the levels of the other antiviral and risk resistance.

The big issue with ritonavir is drug interactions. It strongly inhibits CYP3A4 and can raise levels of statins, benzodiazepines, certain heart medicines, and many other drugs. That can cause dangerous side effects like muscle breakdown with some statins or too much sedation with some sleeping pills. Always give your provider a complete medication list, including over-the-counter drugs and herbal supplements like St. John's wort.

Your doctor will monitor weight, lipids, and liver function. Blood tests help spot problems early so doses or medicines can be adjusted. If you have diabetes or high cholesterol, expect closer follow up. For pregnant people, discuss risks and alternatives — some regimens change in pregnancy.

Thinking about buying ritonavir online? Use licensed pharmacies only and require a valid prescription. Avoid sites that sell powerful antivirals without a prescription — fake or substandard drugs are a real risk. Check pharmacy reviews, look for contact info, and prefer pharmacies that require a prescription upload.

If you miss doses, talk to your clinic — advice depends on the drugs in your combo. Report new symptoms like yellowing skin, severe stomach pain, muscle pain, or fainting. Keep medicines stored as directed and bring a list of current drugs to every appointment. Stick with regular care teams; they know how to adjust therapy safely.

Need plain answers? Ask your pharmacist to review interactions before starting any new drug. If you're switching doctors or moving, bring your treatment history and resistance tests if you have them. For trusted reading, sites like WHO, CDC, or national HIV guidelines explain ritonavir use in clear terms. If cost or access is a worry, social services or local HIV clinics often help with medicine access programs.

Remember: ritonavir is powerful. Used right it protects your treatment. Talk openly with your team about side effects, interactions, pregnancy, and plans for travel so your regimen stays safe and effective and trusted resources.